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Brand Name : Imbruvica
Composition : ibrutinib
Manufactured by : Janssen Pharmaceuticals Ltd.
Strength : 140 mg
Form : Capsule
Packing : Pack of 120 Capsules



Ibrutinib is the generic name for the trade drug Imbruvic. In some cases, Imbruvica health is being used by health care professionals as a trading name while referring to the generic drug name ibrutinib. Ibrutinib is also a cancer medication that interferes with the growth and spread of cancer cells in the body.

Ibrutinib is used to treat certain types of non-Hodgkin lymphoma, including mantle cell lymphoma (MCL), Waldenstrom’s macroglobulinemia, and chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) in people with or without 17p deletion. Ibrutinib is sometimes recommended when other medicines have not been effective on the disease.

Ibrutinib was approved to treat mantle cell lymphoma by the US Food and Drug Administration (FDA) on an “accelerated” basis. In clinical studies, tumors responded to this medicine.

However, it has not been shown that ibrutinib can improve symptoms or lengthen survival time in people with this type of lymphoma. Ibrutinib may also be used for purposes not listed in this medication guide it can further be judged by the physician.


You must follow all the directions given on the medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all the medicines you use.


Before taking IMBRUVICA, inform your healthcare provider about all your medical conditions:

  • In case you have had recent surgery or plan to have surgery in the future. Your healthcare provider may recommend stopping taking IMBRUVICA for any planned medical, surgical, or dental procedure.
  • you have bleeding problem/problems.
  • If you have or felt any kind of heart rhythm problem in past, you have a habit of smoking or have a medical condition like high blood pressure, high cholesterol, or diabetes that increases the risk of heart diseases.
  • If have any kind of infection or have liver problems.

Using ibrutinib may increase your risk of developing other types of cancer, such as skin cancer.

It could harm the unborn baby. You may need to have a negative pregnancy test before starting this treatment.

  • Use effective birth control to prevent pregnancy while you are using this medicine, whether you are a man or a woman.
  • Women, if they are pregnant or plan to become pregnant. IMBRUVICA can harm the unborn baby. Females should not plan pregnancy during treatment and 1 month after the last dose of IMBRUVICA.
  • the women who are breastfeeding or plan to breastfeed. You and your healthcare provider should decide what you need to continue IMBRUVICA or breastfeed.

Do inform your healthcare provider about all the medicines you take, including prescription medicines and over-the-counter medicines, vitamins or any herbal supplements. The doctor must be aware of the medicine his patient is taking for further treatment and its effects.

How should I take ibrutinib?

  • Take IMBRUVICA exactly as your healthcare provider has suggested taking.
  • Take medicine only one time a day as per the schedule fixed.
  • Swallow IMBRUVICA whole capsules and tablets with a glass of water.
  • Do not break, cut, crush, or chew IMBRUVICA tablets.
  • Drink plenty of liquids while you are taking ibrutinib. Remain hydrated
  • If you miss a dose of IMBRUVICA take it as soon as you remember to take it on the same day.
  • If you have taken IMBRUVICA in excess, call your healthcare provider or rush to the nearest hospital emergency room right away.
  • Take IMBRUVICA at the same time each day as per the schedule.

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

What should I avoid while taking IMBRUVICA?

  • You should not drink grapefruit juice, eat grapefruit, or eat Seville oranges (often used in marmalades) during treatment with IMBRUVICA. These products may increase the amount of IMBRUVICA in the blood.
  • You may need to stop using the medicine for a short time.
  • Store at room temperature away from moisture and heat.
  • Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

Take the missed dose on the same day you remember it. Take your next dose at the regular time and stay on your once a day schedule.

Do not take extra medicine to make up the missed dose. Never take 2 doses on the same day.


Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using ibrutinib and call your doctor at once if you have: chest pain and severe dizziness, fast or irregular heartbeats, trouble breathing, feeling like you might pass out; severe or ongoing diarrhea; fever, swollen gums, painful mouth sores, pain when swallowing, skin sores, cold or flu symptoms, cough, trouble breathing; pale skin, easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin; severe weakness or dizziness, confusion, problems with speech, prolonged headache; signs of bleeding in your digestive tract–severe stomach pain, pink or brown urine, black or bloody stools, or if you cough up blood or vomit that looks like coffee grounds; signs of tumor cell breakdown–lower back pain, blood in your urine; numbness or tingly feeling around your mouth; muscle weakness or tightness; fast or slow heart rate, weak pulse; or kidney problems–little or no urinating; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath.

Common side effects may include 

  • Pale skin,
  • Easy bruising or bleeding;
  • Fever,
  • Chills,
  • Flu symptoms;
  • Nausea,
  • Diarrhoea;
  • Tired feeling;
  • Rash; or
  • Muscle pain,
  • Bone pain.


Usual Adult Dose for Lymphoma:

Initial dose: 560 mg orally once a day

Comment: Dose modifications may be necessary for adverse reactions.

Use: For the treatment of patients with mantle cell lymphoma (MCL) who have received at least one prior therapy.

Usual Adult Dose for Chronic Lymphocytic Leukemia:

Initial dose: 420 mg orally once a day

Comment: Dose modifications may be necessary for adverse reactions.

Use: The treatment of patients with chronic lymphocytic leukemia (CLL) who have received at least one prior therapy or CLL with 17p deletion.

Usual Adult Dose for non-Hodgkin’s Lymphoma:

Initial dose: 420 mg orally once a day

Comment: Dose adjustments of this drug are not required for patients undergoing plasmapheresis; dose modifications may be necessary for adverse reactions.

Use the treatment of patients with Waldenstrom’s macroglobulinemia.

What other drugs will affect ibrutinib?

Other drugs may interact with ibrutinib, including prescription and over-the-counter medicines, vitamins, and herbal products.

To legally purchase this medicine from, you’ll require a prescription from your Registered Medical Practitioner.


The information provided about this medication is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.

Remember, keep this and all other medicines out of the reach of children and away from pets, never share your medicines with others, and use this medication only for the indication prescribed.

The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Note: abtreibungspille kaufen in Deutschland mit Express-Schnellversand

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